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Holy Cow Performance Horses

Sunday, November 30, 2014

Polysaccharide Storage Myopathy (PSSM)

Polysaccharide Storage Myopathy (PSSM) is a dominant autosomal hereditary condition that can cause a genetic form of tying-up with muscle damage and inability to move. One form of PSSM is in part a result of a single base pair substitution in GYS1 gene, thereby changing the amino acid sequence of the glycogen synthase enzyme. At least 20 breeds have been identified with Type 1 PSSM.

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